PRO-MINE: PROtein Mutations In NEurodegeneration

A bioinformatics repository and analytical tool for TDP-43 mutations.

Background

Help

INPUT

Enter the mutations of interest [?]:

-or-

Upload a file with the mutations [?]:

Use TDP-43 mutations core set [?]

PREDICTION OF MUTATIONAL EFFECTS ON PROTEIN FUNCTION

Select the Prediction tools to be used: [?]

NetPhos
PolyPhen
SIFT
SNAP

Send results to the following email:

[An email containing a link to the results will be sent to you as soon as the results are processed.
This is recommended when submitting a large number of mutations.]

-or-

PROTEIN SEQUENCE ANNOTATION WITH MUTATIONS

Select the organisms:

Homo sapiens
Pan troglodytes
Mus musculus
Rattus norvegicus
Gallus gallus
Xenopus tropicalis
Danio rerio

[The protein sequences of the selected organisms will be aligned.]

Enter the number of the exons to display, separated by comma:

[Full protein sequences will be displayed if no exons are specified.]

Number of aminoacids to be displayed per row: